ABSTRACT
Gastric yolk sac tumors are extremely rare and their prognosis is poor; most patients have widespread metastases at the time of diagnosis. The treatment of gastric yolk sac tumors consists of aggressive chemotherapy combined with radiotherapy and surgery. Here, we first report a case of gastric yolk sac tumor presenting as an early gastric cancer that was cured after a gastrectomy with lymphadenectomy.
Subject(s)
Humans , Male , Middle Aged , Biopsy , Endodermal Sinus Tumor/blood , Gastrectomy , Gastroscopy , Immunohistochemistry , Lymph Node Excision , Stomach Neoplasms/blood , Tomography, X-Ray Computed , Treatment Outcome , alpha-Fetoproteins/analysisABSTRACT
This is a case report of an endodermal sinus tumour arising in the stomach of a 1 1/2 years male child. The tumour occupied full thickness of fundus and part of the body of the stomach. H&E sections of the tumour tissue showed endodermal sinus tumour with predominantly reticular and endodermal sinus patterns. Elevated level of alpha-fetoprotien was detected in the serum of the patient and within the tumour tissue by immunohistochemical technique.
Subject(s)
Diagnosis, Differential , Endodermal Sinus Tumor/blood , Humans , Infant , Male , Stomach Neoplasms/blood , alpha-Fetoproteins/metabolismABSTRACT
Yolk sac tumors are common in children. By virtue of being chemosensitive, they are amenable to cure by chemotherapy alone and radical surgery is often not required. Yolk sac tumors occurring in the vagina are rare and thus may not be recognized early or may be inadvertently subjected to radical surgery. The authors report a case that presented to them after radical surgery with elevated Alpha-fetoprotein level is reported. The management of this case and review of the relevant literature are discussed here.